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含氟生物醫(yī)藥材料

含氟生物醫(yī)藥材料具有一些特殊的物理化學(xué)性質(zhì),在醫(yī)藥工業(yè)中有非常重要的應(yīng)用。每年上市的新藥中,大約有15-20%都是有機(jī)氟化合物。因藥物中結(jié)合的氟原子進(jìn)入生物體的代謝系統(tǒng)不易受到分解和代謝的屏蔽效果,又具有高電負(fù)性會產(chǎn)生極性效果,這些效果的組合增加了化合物的生理活性作用,從而促使藥效顯著增加。由于含氟有機(jī)化合物具有特異的生物活性和生物體適應(yīng)性,含氟藥物的療效比一般藥物均強(qiáng)好幾倍。 世界上已商品化和正在開發(fā)的含氟醫(yī)藥有近百種。重山光電正全力打造含氟生物醫(yī)藥材料系列生產(chǎn)線,目前在建的產(chǎn)品生產(chǎn)線主要包括全氟萘烷、全氟辛烷、全氟三丙胺、全氟三丁胺、全氟溴辛烷等系列產(chǎn)品。

Fluorine-containing biomedical materials have some special physical and chemical properties and have very important applications in the pharmaceutical industry. About 15-20% of new drugs produced each year are organic fluoride. Because the fluorine atoms in the drug are not easily screened by decomposition and metabolism when they enter the organism, and the fluorine atoms have high electronegativity and good effects, which increases the physiological activity of the drugs, promotes the efficacy of the drugs. Due to the special biological activity and adaptability of fluorinated organic compounds, the curative effect of fluorinated drugs is several times stronger than that of general drugs. There are nearly 100 kinds of fluorine-containing medicines which have been commercialized and are being developed in the world. We are making efforts to build a series of fluorine-containing biomedical materials production lines. Currently, these product lines are being constructed, including perfluorodecalin, perfluorooctane, perfluorotripropylamine, perfluorotributylamine, perfluorooctyl bromide.

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